Primary diffuse leptomeningeal oligodendroglioma.

vealed elevated protein level of 72 mg/dl and 3 white blood cells with no neoplastic cells, therefore providing no evidence of malignancy or CNS infection. Antiepileptic medications were started, and the patient underwent a right temporal brain and leptomeningeal biopsy. Pathology revealed idiopathic leptomeningeal inflammation and fibrosis without brain involvement. The patient improved clinically, but she returned multiple times over a 3-month period with intermittent ataxia, confusion, headaches and emesis. A ventriculoperitoneal shunt was placed for progressive ventriculomegaly. Serial imaging showed improvement in the hydrocephalus after cerebrospinal fluid diversion, but progressive leptomeningeal enhancement of the brain and spinal Case Illustration